Products

AlfaSIP™ - Sanitization & Disinfection Kit
                    for Processing Equipment

AlfaSIP™ A new, rapid, in-situ kit to provide sanitization of the Alfa Wassermann Pilot Scale eKII / KII and ePKII / PKII Production Scale Continuous Flow Ultracentrifuges, AW Promatix 1000™ BioPurification System and other processing equipment without the use of heat.

Sanitization In Place in a closed system for total protection

Disinfectant, sanitizer and virucide

Compatible with stainless steel, most plastics & elastomers

Short sanitization time (5-10 minutes) with no heating-cooling cycle

Simple procedurefor centrifuges, chromatography and ultrafiltration systems and general laboratory surfaces

The first product in the series, AlfaSIP-50D, is aimed at disinfection and sanitization in place. The AlfaSIP-50D kit produces a >99% pure solution of chlorine dioxide in water. It is manufactured for Alfa Wassermann and produces the ClO2 in a patented, membrane-based micro-reactor envelope.

To generate the solution, the envelope containing the reagents is simply added to water. Pure chlorine dioxide is produced without the need for any capital equipment and the solution reaches the required strength after a few hours. It is then pumped into the centrifuge and resides for 5-10 minutes before rinsing.

FAQs about pure Chlorine Dioxide and the AlfaSIP™-50D kit

How many ultracentrifuges will the AlfaSIP-50D kit treat?
The kit produces 50 liters of disinfecting /sanitizing solution at 100 ppm. About 5-6 liters are required to sanitize an Alfa Wassermann Continuous Flow Ultracentrifuge so one kit is enough to treat 4-5 machines before and after every run.

Once the AlfaSIP solution has been made, for how long is it usable?
The solution remains usable at the correct strength for 15 days after production from the AlfaSIP-50D kit.

What strength of solution is necessary for disinfection / sanitization?
The AlfaSIP-50D kit produces 50 liters of chlorine at 100 ppm, which requires a 10-minute disinfection protocol. The activated gas attacks S-S bonds in biological structures and little else, so smaller quantities at lower concentrations (compared with many other disinfecting agents) are necessary.

How about sanitization of ultrafiltration and chromatography systems?
The solution from the AlfaSIP-50D kit can be used to sanitize ultrafiltration systems. It passes through membranes (even RO) providing simultaneous disinfection on both sides. Depending upon the specific media and buffers, the AlfaSIP-50D kit can also be used to sanitize some chromatography systems. For example, Phosphate Buffered Saline, Acetate and TRIS are entirely compatible with AlfaSIP. It is always recommended that users first check compatibility with the manufacturer of the equipment to be sanitized.

What other uses does AlfaSIP have?
The solution from the AlfaSIP-50D kit can be used at 100 ppm to sanitize other laboratory equipment such as centrifuges, biosafety cabinets, incubators and cold rooms. At 50 ppm strength, it is used for disinfection of the coolant loop on the AWST ultracentrifuges. At the 20 ppm level, it can be used to sanitize and clean hard lab surfaces.

Since AlfaSIP is a chlorine dioxide product, does it create or employ chlorine or oxidize by chlorinating?
AlfaSIP-50D does NOT contain nor produce chlorine, hypochlorous acid or bleach! In fact, the chemical reaction producing the chlorine dioxide prevents the production of free chlorine.

Is AlfaSIP harmful to equipment?
Continuous exposure at ambient temperature (22ºC/72ºF) of 304L and 316L stainless steel up to 550 ppm chlorine dioxide, in both welded and non-welded condition, is not expected to produce any discernable corrosion. Chlorine dioxide produced by the AlfaSIP-50D kit is also compatible with most plastics and elastomers at recommended application concentrations and contact times. The keys are the solution's non-acidity and efficacy at comparatively low concentrations and the inherent lower aggressiveness (oxidizing potential) of chlorine dioxide compared with many other oxidizers.

Does AlfaSIP have to be neutralized at disposal?
Unlike sodium hydroxide, AlfaSIP-50D solution does not need to be neutralized and can usually be drained into local sewers. Check first with local environmental authorities. Dispose spent envelope according to label instructions or send it with other chemicals for disposal.

What is the difference between stabilized chlorine dioxide and AlfaSIP?
The term 'stabilized chlorine dioxide' is misleading. Formulations so-named contain sodium chlorite and activating agents that react to release chlorine dioxide slowly, producing low concentrations of ClO2 at an acidic pH and containing high levels of the chlorite ion (ClO2-) that remain in solution. Because the small quantity of chlorites present in the AlfaSIP-50D envelope cannot escape into the activated solution, AlfaSIP is generally compatible with most materials, and effective in oxidizing.:

Example solution analysis:

In what conditions is AlfaSIP not appropriate?
The conditions to avoid (those which can degrade AlfaSIP) are:
- The presence of readily-oxidizable substances
- A pH of <3 or >10
- The presence of reducing agents such as NaHSO4
- Temperatures above 35ºC (95ºF)

To discover how AlfaSIP™ can benefit you, please meet us at the leading exhibitions and congresses.
Find the list here...

Download your copy of
the AlfaSIP brochure in Letter format for the US and A4 format for International.

See also the Technical Note AlfaSIP™ - Sanitization by Pure Chlorine Dioxide

A number of Free Trial Kits
are now available.
Please contact us.

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